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Clotof (Clobetasol)

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Clotof is steroidal medicine that reduces swelling of many skin conditions. It is used to reduce immune-responsive skin diseases such as psoriasis, eczema, etc. It works by reducing the swelling, redness, rash and itching at the affected site.

Other names for this medication:
Agiclob, Betalic, Betanate, Clobadis, Clobate, Clobecos, Cloberis, Clobesym, Clobet, Clobetamil, Clobetasol, Clobevate, Clobex, Clobezine, Clobin, Clomad, Clomax, Clomic, Clonate, Cloriv, Clovate, Cortaz, Cosvate, Covate, Cutivate, Cvate, Eavone, Ecziclo, Embeline, Etavone, Gracederm, Hinate, Isovate, Kloryl, Klosol, Lobate, Magclo, Miclogenta, Miconit, Monosol, Salyco, Sonaderm, Steriderm, Steridom, Taxalic, Tenovate, Tigerderm, Topifort, Topisal, Zincoderm

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Also known as: Clobetasol


Clobetasol is a highly potent steroid that helps reduce inflammation in the body.

Clotof (for the skin) is used to treat inflammation and itching caused by plaque psoriasis or skin conditions that respond to steroid medication.


Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Do not take by mouth. Topical medicine is for use only on the skin. Rinse with water if this medicine gets in your eyes or mouth.

Do not use Clotof on broken or infected skin. Also avoid using this medicine in open wounds.

Wash your hands before and after using clobetasol, unless you are using the medicine to treat the skin on your hands.

Apply a thin layer of medicine to the affected skin and rub it in gently. Do not apply this medicine over a large area of skin unless your doctor has told you to.

Do not cover the treated skin area with a bandage or other covering unless your doctor tells you to. Covering treated areas can increase the amount of medicine absorbed through your skin and may cause harmful effects.

If you are treating the diaper area, do not use plastic pants or tight-fitting diapers.

This medicine is for short-term use only (2 weeks, or up to 4 weeks for scalp psoriasis). Follow your doctor's dosing instructions very carefully.

If you use clobetasol to treat plaque psoriasis, you should stop using the medicine once your skin symptoms are controlled.

Call your doctor if your symptoms do not improve, or if they get worse.

You should not stop using clobetasol suddenly. Follow your doctor's instructions about tapering your dose.

Store at room temperature away from moisture and heat. Keep from freezing.

Clobetasol foam is flammable. Do not use near high heat or open flame. Do not smoke until the foam has completely dried on your skin.

Detailed Clotof dosage information


Generic Clotof is not expected to cause overdose symptoms. But long-term use of high Generic Clotof doses can lead to symptoms such as: thinning skin, easy bruising, changes in the shape or location of body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.


Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Store the foam can or spray bottle at room temperature, away from heat, flames, smoke, and direct light. Do not keep this medicine inside a car where it could be exposed to extreme heat. Do not poke holes in the canister or throw it into a fire, even if the canister is empty.

Store the Clotof® E cream at room temperature, away from heat, moisture, and direct light. Do not refrigerate. Keep Clotof® E cream and Impoyz™cream from freezing.

Detailed Clotof E dosage information

Side effects

The most common side effects associated with Clotof are:

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Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of clobetasol topical cream, foam, gel, ointment, or scalp solution in children 12 years of age and older. However, because of this medicine's toxicity, it should be used with caution. Children may absorb large amounts through the skin, which can cause serious side effects. If your child is using this medicine, follow your doctor's instructions very carefully. Safety and efficacy have not been established in children younger than 12 years of age and the use of clobetasol topical cream, foam, gel, ointment, or scalp solution is not recommended. The safety and efficacy of clobetasol topical lotion, shampoo, or spray have not been established in children and use is not recommended.

Appropriate studies have not been performed on the relationship of age to the effects of Impoyz™ cream in the pediatric population. Safety and efficacy have not been established and use in children is not recommended.

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