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Epivir (Lamivudine)
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Epivir

Epivir once daily in combination with at least 2 other HIV ARVs for 28 days is a first-choice regimen for post-exposure prophlaxis (PEP) in people with kidney problems. PEP is used to prevent HIV infection in people who do not have HIV, and think they have been exposed to HIV. PEP must be started within 72 hours of the exposure.

Other names for this medication:
Abamune, Combivir, Duovir, Emduo, Emtri, Haptavir, Hepavud, Hepitec, Hepravir, Hivir, Ladiwin, Lamidac, Lamistar, Lamivir, Lamivox, Lamivudine, Lamostad, Lamuvid, Lavir, Lazid, Lmivir, Nevilast, Shanvudin, Stadin, Stavex, Tenola, Tenolam, Tenvir, Trimune, Trioday, Virolam, Virolis, Zidolam

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Also known as: Lamivudine

Description

Epivir is used to treat HIV, which causes the acquired immunodeficiency syndrome (AIDS). Epivir is not a cure for HIV or AIDS. Epivir is used to treat chronic hepatitis B. Epivir works by blocking the ability of the hepatitis B virus to multiply and infect new liver cells. Epivir is also known as Lamivudine, Lamivir, Zeffix, Heptovir. Generic Name of Epivir is Lamivudine. Brand names of Epivir are Epivir, Epivir HBR.

Dosage

This section provides information on the proper use of a number of products that contain lamivudine. It may not be specific to Epivir A/F. Please read with care.

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

This medicine comes with a patient information leaflet. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Epivir® and Epivir-HBV® both contain the same medicine, but Epivir® has more medicine in each tablet or dose of liquid. Use only the brand of this medicine that your doctor prescribed. If you have HIV or AIDS, you need to use Epivir®. If you have hepatitis B but you do not have HIV or AIDS, you can use Epivir-HBV®.

Your doctor may want to test you for HIV before you start using Epivir-HBV® and during your treatment. Your medicine may need to be changed based on these test results.

It is important to take Epivir® as part of a combination regimen. Take all of the medicines your doctor prescribed at the right time of day. This will make your medicines work better.

Keep using lamivudine for the full time of treatment, even if you or your child begin to feel better. Do not stop using it without checking first with your doctor. When your supply of the medicine is running low, contact your doctor or pharmacist ahead of time. Do not allow yourself to run out of the medicine.

If you are using the oral liquid, use a specially marked measuring spoon, dosing syringe, or medicine cup to measure each dose accurately. The average household teaspoon may not hold the right amount of liquid.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (solution or tablets): For treatment of hepatitis B infection: Adults—100 milligrams (mg) once a day. Children 2 to 17 years of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 3 milligrams (mg) per kilogram (kg) of body weight per day. The doctor may increase your dose as needed. However, the dose is usually not more than 100 mg per day. If your child cannot swallow the tablets, he or she may take the oral liquid. Children younger than 2 years of age—Use and dose must be determined by your doctor. For treatment of HIV infection or AIDS: Adults—300 milligrams (mg) once a day or 150 mg 2 times a day. Children 3 months of age and older— Solution: Dose is based on body weight and must be determined by your doctor. The dose is usually 5 milligrams (mg) per kilogram (kg) of body weight taken 2 times a day, or 10 mg per kg once a day. The doctor may increase your dose as needed. However, the dose is usually not more than 300 mg per day, taken with other HIV medicines. Tablets: Dose is based on body weight and must be determined by your doctor. The dose is usually 150 to 300 mg per day. If your child weighs 14 kg or more, it is preferred that he or she take the scored tablet. Children younger than 3 months of age—Use and dose must be determined by your doctor.

Note: Patients that require treatment for both hepatitis B and either AIDS or HIV should follow the dosing schedule for HIV or AIDS.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Lamivudine dosage information

Side effects

The most common side effects associated with Epivir are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Be careful with Epivir while you are pregnant or have nurseling. Epivir can pass in breast milk and harm your baby. Do not use Epivir if you are allergic to Epivir components. Do not use Epivir together with Combivir (medication that contains a combination of lamivudine and zidovudine). Be careful with Epivir if you have used a medicine similar to Epivir in the past such as abacavir (Ziagen), didanosine (Videx), stavudine (Zerit), tenofovir (Viread), zalcitabine (Hivid) or zidovudine (Retrovir). Be careful with Epivir if you have kidney disease, liver disease, history of pancreatitis. Use latex condom while having sex. Avoid alcohol. Do not stop taking it suddenly.

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A 2-round Delphi technique, involving an expert panel of physicians who are members of the drug regulatory agency, was used to evaluate the satisfaction with drug therapy for selected indications. Attitudes of doctors were predicted by post-attachment attitudes, which in turn were predicted by encouragement from consultants and influences of specialist registrars during the attachment at medical school. As immunohistochemistry demonstrated overlapping expression of specific connexins in keratinocytes, we performed colocalisation analyses and applied a modified FRET methodology to assess possible heteromeric interactions between different combinations of four wild-type (wt) and mutant connexins. Autoimmune hepatitis is a rare, chronic inflammatory disorder which has been associated with a number of other auto-immune conditions. Germline mutations or large-scale deletions in the singulair asthma medicine cost coding region and splice sites of STK11/LKB1 do not account for all cases of Peutz-Jeghers syndrome (PJS). Developmental abnormalities in early-onset hydrocephalus: clues to signalling.

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The Munich-Composite International Diagnostic Interview was used to assess social phobia and paranoid symptoms, along with data on social phobia features. This study examined the presence and stability of morning cortisol levels and slopes (i.e., cortisol awakening response or CAR) in a sample of 2-4year old children in out-of-home child care with working mothers. Computational elastography from standard ultrasound image sequences by global trust region optimization. No significant haemodynamic abnormalities were observed during the period of intraoperative ECG changes. Hypomorphic mutations in Smn reduce dSMN protein levels in the adult thorax, causing flightlessness and acute muscular atrophy. Velocity of propagation of electrical excitation in the heart is important for the understanding of complex arrhythmias such as ventricular fibrillation (VF). Fractures of the medial humeral epicondyle in child: preliminary study about 18 cases. A MOLECULAR REEXAMINATION OF DIPLOID HYBRID SPECIATION OF SOLANUM RAPHANIFOLIUM.

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Alendronate as an effective effexor medication dose countermeasure to disuse induced bone loss. We also analyzed patients with benign lung disease, premalignant disease, and a known history of heavy smoking. Comparisons are made between the height of the frond base infected, the number of frond bases infected, and subsequent development of basal stem rot. In the present paper the crossover sites of six additional strains were examined by RFLP analysis. Use of nutritional supplements among Mexican women and the estimated impact on dietary intakes below the EAR and above the UL. The purpose of this retrospective study was to examine the clinical and radiographic results of treatment of proximal scaphoid nonunion and avascular necrosis with vascularized bone graft from the distal part of the radius in adolescent patients. Microsurgical fenestration of the third ventricle floor combined with stoma stenting can be a viable option for hydrocephalus control.

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The D360P mutation decreased transaminase activity and was more specific in catalyzing beta-decarboxylation reaction. Compared to children with CGHD without midline defects, those with ONH/SOD presented with greater height, weight, and BMI SDS. Laparoscopic surgery was performed via one principal and two ancillary ports. Preoperative assessment included physical and proctologic examination. The cysteines of the extracellular loop are crucial for trafficking of human organic cation transporter 2 to the plasma membrane and are involved in oligomerization. This study concludes that extraamniotic Foley catheter balloon is an effective, safe, simple, low-cost, reversible, non-pharmacological mechanical method of preinduction cervical ripening.

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The anti-proliferative effect of the BM-MSCs from healthy donors was tested also on transformed B-cell lines as a model of non-antigen-stimulated lymphocytes. The new derivatives were evaluated for in vitro antimycobacterial activity against Mycobacterium tuberculosis H37Rv. The assessment of co-morbidities during waiting time is important as well as evaluating how the co-morbidity may affect the final outcomes of the total joint replacement. Significant heritabilities for all traits were detected in both populations. Antinociceptive Activity of Methanol Extract of Tabebuia hypoleuca (C. These nucleolar caps have been proposed to arise from the segregation of nucleolar components. GENETIC DRIFT AND FOUNDER EFFECT IN NATIVE VERSUS INTRODUCED POPULATIONS OF AN INVADING PLANT, LYTHRUM SALICARIA (LYTHRACEAE).

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The anatomy of the gubernaculum and the effect of spermatic vessels ligation on the collateral circulation were studied in 90 boys with 100 abdominal testes with a short pedicle. The effect of aortic dissection on outcome in descending thoracic and thoracoabdominal aortic aneurysm repair. Gestational diabetes mellitus and neonatal hyperthyrotropinemia. Hence, the microtubule-nucleating sites may possess a relatively labile control specifying 15 protofilaments superimposed upon that for maintaining 13-protofilament fidelity. The challenges in this case were the absence of a stiff region elocon reviews to anchor the percutaneous valve, the lack of radiographic landmarks and the difficulties of precise annulus measurements. Finally, various procedures useful in the isolation, separation, and quantitation of these alkaloids, as well as their biosynthesis and synthesis, are also cited. Age- and sex-specific bandings for the total problem score reflected small differences between homogeneous subgroups. This study explored the attitudes of health practitioners who provide healthcare to PLHIV towards THR. Since such haplotype maps reveal the polymorphisms due to single nucleotide differences (SNPs) and small insertions and deletions (RFLPs), they are useful in association studies, studies involving genomic instabilities in cancer, and genetics, and yet incur relatively low cost and provide high throughput. Historically, most streams and lagoons were highly seasonal, but those now used for the delivery of irrigation water maintain elevated flows and increased turbidity and nutrient loading.

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Primary sclerosing cholangitis was associated with a four-fold increase in mortality in this population-based study. Major depressive disorder (MDD) is characterized by disturbances in affect, motivation, and cognitive control processes, including error detection. MIDAS (Medical information and documentation automated system)--application of the program ARDIS-Minsk in therapeutic and preventive care. IL-6 enhanced LGL NK activity in a dose-dependent manner against K562, however IL-2 was a more potent stimulus of LGL NK function. Moreover, future research can aim at understanding the reasons that lead women to opt for midwife-led prenatal care.

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The purpose of this study was to evaluate retrospectively the indications, surgical technique, and postoperative findings in a series of 35 patients presenting lumbar canal stenosis due to osteoarthritic degeneration who underwent surgery using a tubular system for muscle retraction. This approach is able to automatically register the object surface to its counterpart in image volume. In addition, important aspects of the calibration and low energy extrapolation techniques for the microdosimetric spectrum are provided. The present case showed adverse effects of MTX therapy may occur even after years of continuous treatment. The incidence of the heat illness is closely associated with body temperature regulation, which is much affected by body fluid state in humans. Biological properties of factors secreted by antigen-reactive suppressor cells in mice infected with Mycobacterium lepraemurium. Effects of chronic treatment with the leukotriene D4-antagonist compound LY171883 on B6C3F1 mice. The data was collected using an interview technique with form registration, active search in medical records, Scale of Mode of Confronting Problems and Inventory of Anxiety and State.

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To provide a systematic review and meta-analysis of studies comparing ureterolithotripsy (URS) with percutaneous nephrolithotripsy (PCNL) or laparoscopic ureterolithotomy (LU) techniques for the management of large proximal ureteral stones (diameter greater than 10 mm). The reconstruction process can be complicated further by unpredictable factors how often can i take zofran 8 mg . Toxorhynchites moctezuma was much less susceptible to temephos than the Ae. Overall, besides nearly doubling the number of current proteins, the predicted GOS proteins also add a great deal of diversity to known protein families and shed light on their evolution. Our objective was to determine the seroprevalence of HCV antibodies in healthy pregnant women and to assess the potential risk factors for HCV infection in HCV positive subjects and in the control group. Vasodilator therapy for angina pectoris: the intersection of homeopathy and scientific medicine. The fusion protein bound to human monocyte-derived dendritic cells and was internalized into early endosomes. This perspective considers how the unique anatomy and physiology of the retina may predispose it to the metabolic stresses of diabetes.

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We also conducted individual interviews with participants after study completion. As in ECD, even-electron d/w ion series dominate the spectra, but we also detect numerous a/z (both even-electron and radical species), (a/z - B), c/x, (c/x - B), and (d/w - B) ions with minimal nucleobase loss from the precursor ions. Use of a geographic information system to identify differences in automated external defibrillator installation in urban areas with similar incidence of public out-of-hospital cardiac arrest: a retrospective registry-based study. moduretic 25/2 5 mg Confluent cells were irradiated with 12C-beam at various doses using 15UD Pelletron accelerator. The polarizable force field is based on a minimal set of fitting parameters, it accounts for the dielectric screening arising from ions and electrons separately, and it can be easily implemented in any software for atomistic molecular dynamics simulations. Results were limited by small sample sizes, lack of rigorous methodology, short follow-ups, and the limited number of published studies.

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PNS involvement is common in FD and should be suspected in patients exhibiting an acrosyndrome, dyshidrosis and/or cold hypoesthesia. Forty eyes were identified with epiretinal membranes (33 eyes) or contraction-induced choroidal folds (seven eyes). We determined the hospitalization and ambulatory care expenses incurred by an Argentine health insurer for the hospitalization of diabetic clients during the study period, and compared these expenses to the expenses of insured diabetics who were not hospitalized during that period. Several models describing this relationship are proposed and associated estimated parameters are given. It seems biasing phenotypes toward the male optima has serious fitness costs for females. This article calculates the mean percentage change in various measures of nursing staff in Pennsylvania hospitals, 1991-1997, and the percentage of hospitals that experienced various degrees of this change. In the early (pre-necrotic) period of injury these changes were insignificant. Although in close proximity to blood vessels, migrating neuroblasts are separated from endothelial cells by 1-2 layers of astrocytic processes, as revealed by electron microscopal studies of retrovirally labeled postnatally born cells. Data analysis consisted in comparison of proportions with the chi-squared test.

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