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Nimodipine

Nimodipine is a medicine used to treat and prevent further damage to the brain after bleeding around the brain (subarachnoid hemorrhage or SAH). It is known as a calcium channel blocker and helps to improve blood flow to the brain and prevent changes in brain function.

Other names for this medication:
Modipin, Modipine, Nimocer, Nimodip, Nimodipine, Nimotide, Nymalize, Vasotop

Similar Products:
Ticlid, Mircette, Temovate, Zyprexa, Remeron, Lozol, Reminyl, Risperdal, Naprodom, Apetone, Metclam, Noroxin, Qiftrim, Bronkonil,

Description

Nimodipine is used to treat symptoms resulting from a ruptured blood vessel in the brain (subarachnoid hemorrhage). It works by increasing the blood flow to injured brain tissue.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain nimodipine. It may not be specific to Nimodipine. Please read with care.

Take this medicine exactly as directed even if you feel well and do not notice any symptoms. Do not take more of this medicine and do not take it more often than your doctor ordered. Do not miss any doses.

This medicine is usually given within 96 hours of having the condition. It is best to take this medicine at least 1 hour before or 2 hours after a meal.

If the capsule cannot be swallowed or if you are using this medicine with a nasogastric tube (NGT), you may put a hole in both ends of the capsule and remove its contents using a syringe. Use the syringe to give the medicine orally or through the NGT. Do not use it to give the medicine as an injection through the veins, muscles, or skin.

If you are using the oral liquid:

Measure your dose with a marked measuring spoon, oral syringe, or medicine cup. If the medicine is going to be given through a nasogastric or gastric tube, use the oral syringe that comes with the package to measure the dose. For each dose, refill the syringe with saline solution to flush any remaining medicine in the nasogastric tube into the stomach.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For subarachnoid hemorrhage: For oral dosage form (capsules): Adults—60 milligrams (mg) or two 30 mg capsules every 4 hours for 21 days. Children—Use and dose must be determined by your doctor. For oral dosage form (solution): Adults—20 milliliters (mL) (60 milligrams [mg]) every 4 hours for 21 consecutive days. Children—Use and dose must be determined by your doctor.

Overdose

If you overdose Nimodipine and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Nimodipine overdosage: pain of chest, fainting, abnormal slow or fast heartbeat, slurred speech, dyspnoea, feeling lightheaded, coma, confused mental state, weakness.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not refrigerate the oral liquid.

Detailed Nimodipine dosage information

Side effects

The most common side effects associated with Nimodipine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies have not been performed on the relationship of age to the effects of nimodipine in the pediatric population. Safety and efficacy have not been established.

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The obese phenotype was not associated with overexpression of GLUT 4 mRNA in gastrocnemius muscle. Glucose-sensitive (GS) neurons decreased in activity during bar pressing and/or during the ingestion period. Given that depression in humans has been linked with social stress, the chronic social stress paradigms for modeling psychiatric disorders in animals have thus been developed. Cellular Antioxidant and Anti-Inflammatory Effects of Coffee Extracts with Different Roasting Levels. Negative pressure stimulates proliferation of granulation tissue, provides a continuous evacuation of fluid and effectively cleans wound surface. pylori eradication in a comparative three-armed randomized clinical trial. Maximal oxygen uptake (VO2max) and maximal numbers of sit-ups, push-ups, and chin-ups and 3-km running time were tested in 107 male infantry soldiers at the beginning and end of basic training (BT), and again at demobilization. Sensitivity for identifying BRCA gene mutation carriers is similar for experienced risk counselors and the computer model BRCAPRO. The frequency of having ever undergone a screen was compared between the two groups.

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The anthropogenic inputs of industrial effluents mainly control the trace metals enrichment in the Cochin estuary. The simulation demonstrates that light absorption could be enhanced significantly in a long wavelength region of the solar spectrum, based upon the localized surface plasmons generated around metal NPs. Calcium chelation and sonication experiments suggested that the presence of inhibitors and the physical configuration of membrane-bound tissue factor in amniotic fluid might explain the modest reduction in tissue factor procoagulant activity relative to total antigen levels observed in vivo. T-cell depletion of the donor bone marrow offers the most effective approach yet reported to prevent graft-versus-host disease and its associated mortality. Changes in the haematopoietic progenitor cell compartment in the acquired immunodeficiency syndrome.

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These changes could contribute to the reduced red cell deformability associated with severe malaria. Analyzed are the ways of validating the modern docking tools and their combinations with different scoring functions. Population-based study of erectile dysfunction and polypharmacy. Nucleosome binding and histone methyltransferase activity of Drosophila PRC2. VP22-Tk-GFP was cloned into lenti- and adenoviral vectors and used for expression studies, analyses for VP22-mediated protein spreading, and to study the effect of VP22 to thymidine kinase/ganciclovir-mediated cytotoxicity. Automated mouse euthanasia in an individually ventilated caging system: system development and assessment. Attenuation of amphotericin-B nephrotoxicity in the candidiasis rat model. In parallel experiments with the passage of Yersinia through Infusoria and mammalian macrophages an analogy to the processes of phagocytosis has been established. The maximum tolerated dose was 58.09 MBq/kg (1.57 mCi/kg) 131I-chTNT-1/B MAB. Most of those pathological conditions are specific and different among different patients, such as bone defects due to traumatic injuries or bone remodeling alterations due to congenital diseases.

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The distribution of responses observed in control treatments was analyzed, with the goal of understanding the implication of this variability on the sensitivity of the OECD 210 test guideline and providing recommendations on revised experimental design requirements of the test. Confluent monolayers of Lulo cells were incubated with promastigotes and adhesion was assessed using both light microscopy and scanning electron microscopy. We have performed intraoperative isotopic infusions of carbon 14-labeled leucine is it bad to take zyrtec with alcohol in 65 patients to define the abnormalities in protein metabolism at both the whole-body and tissue level in patients with weight-losing and non-weight-losing cancer. The presence of the FGFR4-388Arg variant was determined in 114 formalin-fixed, paraffin-embedded lung SCC tissue samples by DNA genotyping and was correlated with clinicopathologic data. We demonstrate that extracellular signal regulated kinases (ERKs) 1, 2, and p38 are rapidly and transiently activated in response to injury in C2C12 cells, and are primarily localized to cells adjacent to the wound bed. Expression of VEGF and Ve-CAD had a similar pattern in all animals, with a significant increase from the inner to the outer part of the meniscus. The Implementation of a Telephone-Delivered Intervention for Asian American Disordered Gamblers: A Pilot Study. The aim of this study was to evaluate whether the use of enamel matrix proteins with or without the use of deproteinized bovine bone influences bone formation when used as an adjunct to guided bone regeneration (GBR). The reason is that the category of node number seems not to be appropriate and will be influenced by the extent of lymph node dissection.

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Comparative evaluation of prevalence of infections caused by hepatitis B and C viruses among individuals of various groups with high risk of infection. Transvascular angiography of the vertebral and spinal venous plexus (directed vertebrovenography). The changes were almost linear between 1 and 2 minimal erythema doses (MED), whereas the change from 2 to 3 MED was less pronounced. The advent of molecular techniques, mainly DNA sequencing, has led to important changes in the taxonomy of pathogenic fungi and a better understanding of the phylogenetic relationships among them. Specifically, in subjective refraction, all patients achieved visual acuity from 7/10 to 9/10 with up to -2.50 cyl. Enhanced gene transfer efficiency in the murine striatum and an orthotopic glioblastoma tumor model, using AAV-7- and AAV-8-pseudotyped vectors. It is possible that Actinomyces odontolyticus has contributed to prosthesis infection in this case. We found that Six3 expression was specifically reduced in lenses of Pax6 heterozygous mouse embryos. Diabetes mellitus (DM) is an acknowledged risk factor for atherosclerosis, and diabetics are more likely to have hypertension. Using Epidemiological Catchment Area data to estimate the population base rates of both alcohol and other substance use disorders biaxin dose allowed for heritability analyses that showed genetic factors to have only a modest influence on overall risk in both sexes (heritability estimates of approximately 0.35 for male subjects and 0.24 for female subjects).

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The data are consistent with centrally mediated anorexia with nutritionally mediated muscle wasting but with visceral hypermetabolism, protein accumulation, and cell proliferation. The biological behavior of colorectal carcinoma in young patients. The reproducibility of measuring the anorectal angle in defecography. AP activity is increased in a variety of muscle disorders, i.e., myopathies and denervation. The aberrant muscle ascended left-upwards about 10 cm to insert to the inner surface of the pectoralis major near its lower glucophage xr 500 mg price margin. These results suggest that cisplatin or LPS treatment of murine bone marrow-derived macrophages results in increased expression of both released and membrane-associated IL-1 and TNF. Differences for the plasticity of other life history traits investigated between tropical and temperate populations were also found. A total of four infertile males with globozoospermia underwent the conventional ICSI program during the period from 1995 to 1997. Microbial interactions during sugar cane must fermentation for bioethanol production: does quorum sensing play a role?.

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nm23-H1, a tumor metastasis suppressive gene, can reverse tumor metastasis phenotype. A critical step in boosting algorithms involves update of the data sample distribution, however, most existing boosting algorithms use updating mechanisms that lead to overfitting and instabilities during evolution of the distribution which in turn results in classification inaccuracies. For the 43 strains subjected to CGH microarray analyses, the common backbone of the Shigella genome was estimated to contain more than 1,900 open reading frames (ORFs), with a mean number of 726 undetectable ORFs. undalis was greatly reduced after hydrolysis of GS by myrosinase. The CA 19-9 production in this tumor does not appear to be directly correlated to aggressive clinical behavior. We prospectively determined the association of cerebral perfusion with subsequent cognitive decline and development of dementia. However, information on the pharmacological sensitivity of distinct APs to drugs known to alter the function of adipose tissue, especially HIV protease inhibitors (PIs) is scant. To date, several bone-associated proteins (osteopontin, bone sialoprotein, alkaline phosphatase, type I collagen) have been demonstrated in histological sections of vessels obtained from patients with ESRD or calcific uremic arteriolopathy. Clinical features common to severe theophylline toxicity include nausea and vomiting, tachydysrhythmias, metabolic disturbances, seizures, and cardiovascular collapse. Based on our findings, we propose that the L1 protein, likely arranged as capsomeres, stabilizes the viral genome within the subviral complex during intracellular trafficking.IMPORTANCE After internalization, the non-enveloped human papillomavirus virion uncoats in the endosome whereupon conformational changes result in a dissociation of a subset of the major capsid protein L1 from the minor capsid protein L2, which remains in complex with the viral DNA.

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DWI predicts future progression to Alzheimer disease in amnestic mild cognitive impairment. In this work we reported a transcriptome assembly and annotation of T. Respiratory syncytial virus possesses pathogenetic qualities that may be attributed to the interplay of viral tenormin generic drug name and host-specific factors including virus strains of different virulence, size of the inoculum, family history of asthma or airway hyper-reactivity and immunologic anomalies of the host. A unique immunosuppressant, FTY720, selectively induces apoptosis in activated lymphocytes, but not in other hematopoietic cells. Although the introduction of new drug combinations, such as cisplatin plus pemetrexed/gemcitabine, has determined an improvement in the patient quality of life, MM remains a universally fatal disease. This is a post hoc analysis of data from 5 clinical trials that investigate the relationship between the baseline severity of heartburn and the baseline severity of EE. Pseudomonas oleovorans NRRL B-778 accumulated mixtures of poly-3-hydroxybutyrate (PHB) and medium-chain-length poly(hydroxyalkanoates) (mcl-PHAs) when grown on glucose, octanoic acid or oleic acid, whereas growth on nonanoic acid or undecanoic acid resulted in copolymers of poly-3-hydroxybutyrate-co-3-hydroxyvalerate (PHB-co-HV). A new classification approach for comparing two active treatments when there is no prior projection on which one is better. Also the patients with light subjective post-phlebitic symptoms declared to feel better.

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