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Symkast (Montelukast)

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Symkast is used to prevent wheezing, difficulty breathing, chest tightness, and coughing caused by asthma in adults and children 12 months of age and older. Symkast is in a class of medications called leukotriene receptor antagonists (LTRAs).

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Also known as: Montelukast


Symkast tablets, produced by Merck Sharp & Dohme, are indicated in the treatment of asthma as add-on therapy in those patients with mild to moderate persistent asthma who are inadequately controlled on inhaled corticosteroids. It helps prevent the wheezing, chest tightness, and shortness of breath caused by asthma and decreases the number of asthma attacks. The medicine is used to prevent exercise-induced bronchoconstriction (narrowing of the air passages in the lungs). It also helps treat seasonal and perennial allergic rhinitis. The active substance contained in the medication is Montelukast, a leukotriene receptor antagonist, that stops leukotrienes, chemical messengers in the immune system, from causing inflammation in the lungs and nose, preventing asthma symptoms and allergies.


Asthma: - Adults (15 years of age and older): 10 mg a day. - Children (6 to 14 years of age): 5 mg a day. - Children (2 to 5 years of age): 4 mg a day. Symkast should be taken once a day in the evening. Exercise-Induced Bronchoconstriction (EIB): - Adults (15 years of age and older): 10 mg a day. - Children (6 to 14 years of age): 5 mg a day. - Children (2 to 5 years of age): 4 mg a day. For prevention of EIB, Symkast should be taken at least 2 hours before exercise. Do not take more than one dose in 24 hours. Allergic Rhinitis: - Adults (15 years of age and older): 10 mg a day. - Children (6 to 14 years of age): 5 mg a day. - Children (2 to 5 years of age): 4 mg a day. For allergic rhinitis, Symkast should be taken once a day. Patients with both asthma and allergic rhinitis should take only one Symkast dose daily in the evening. Pediatric patients are advised to take chewable tablets.


If an overdose occurs and you are feeling unwell, you should seek emergency medical attention or contact your healthcare provider immediately.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Keep your tablets in the blister pack until it is time to take them. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Symkast are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take the Symkast if you are allergic to Montelukast or any of the other ingredients of this medicine. Do not use the tablets to treat an acute asthma attack, including Status Asthmaticus. Do not use the drug if you suffer from severe kidney failure. Do not combine the medication with drugs which induce the CYP450 enzyme system (phenobarbital and rifampin), as they may decrease the effects of Montelukast. Do not use the medication if you have a phenylketonuria, as Symkast contains phenylalanine. Do not take the medication tablets during pregnancy or while breastfeeding without consulting your doctor. Avoid drinking alcohol while taking Symkast tablets, as it may cause excessive drowsiness. Do not give this medicine to children less than 2 years of age.

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